AROME publications PubMed indexed

October 10th, 2014|

2010 Jun 25. PubMed PMID: 20399678.
by AROME webmaster, 10 October 2014

Primary systemic therapy and whole breast irradiation for locally advanced breast cancer: A systematic review

June 16th, 2014|

Orit Kaidar-Person, Abraham Kuten, Yazid Belkacemi, On behalf of AROME
Abstract
The current management of locally advanced breast cancer (LABC) is based on tri-modality treatment including chemotherapy, radiotherapy and surgery. The concept of preoperative concurrent or sequential chemoradiation for LABC was initially reported more than a decade ago; however this concept did not gain popularity because of the low benefit/risk ratio and the lack of strong data supporting the concept.
The purpose of the current systematic review was to explore the published data about preoperative chemoradiation (sequential and/or concurrent)using whole breast irradiation in terms of toxicity and outcome.
by AROME webmaster, 16 June 2014

“The Infinite Maze” of breast cancer, signaling pathways and radioresistance

May 14th, 2013|

“The Infinite Maze” of breast cancer, signaling pathways and radioresistance
Orit Kaidar-Person,Christine Lai,Abraham Kuten,address AROME
Abstract
The parallel growth in our understanding of tumor biology and genetics might be the key to understanding local recurrence after optimal treatment is applied. Data suggest that genetic alterations and breast cancer molecular subtypes have an effect on radiotherapy efficacy and that the HER2, EGFR/PI3K/Akt signaling pathways play a pivotal role in modulation of post-irradiation survival. These pathways have been found to be involved in radiosensitivity and/or radioresistance, tumor cell proliferation, and hypoxia. Therefore, affecting the functional activity of key players combined with radiotherapy might be the future of breast irradiation.
Keywords: Radiobiology, Breast cancer, Radioresistance, Molecular subtypes, Radiotherapy, AROME
by AROME webmaster, 14 May 2013

Therapeutic strategies and mechanisms of tumorigenesis of HER2-overexpressing breast cancer

January 10th, 2013|

Posted by AROME webmaster on January 10, 2013

Therapeutic strategies and mechanisms of tumorigenesis of HER2-overexpressing breast cancer.Emde A, Köstler WJ, Yarden Y; on behalf of AROME. Crit Rev Oncol Hematol. 2010 Oct 15. PMID:20951604

Nasopharyngeal cancer around the Mediterranean area: Role of newer radiation techniques.

January 10th, 2013|

Posted by AROME webmaster on January 10, 2013
Nasopharyngeal cancer around the Mediterranean area: Role of newer radiation techniques.Turkan S, Iğdem S; on behalf of AROME. Crit Rev Oncol Hematol. 2010 Oct 20. PMID:20965745

Optimal sequence of implied modalities in the adjuvant setting of breast cancer treatment: an update on issues to consider.

January 10th, 2013|

Posted by AROME webmaster on January 10, 2013
Optimal sequence of implied modalities in the adjuvant setting of breast cancer treatment: an update on issues to consider. Tsoutsou PG, Belkacemi Y, Gligorov J, Kuten A, Boussen H, Bese …

Post mastectomy radiation for large node negative breast cancer: Time for a second look

January 10th, 2013|

Posted by AROME webmaster on January 10, 2013

Post mastectomy radiation for large node negative breast cancer: Time for a second look.Boutrus R, Taghian AG; on behalf of AROME. Crit Rev Oncol Hematol. 2010 Nov 5.PMID:21115360

Controversies in loco-regional treatment: Post-mastectomy radiation for pT2-pT3N0 breast cancer arguments in favour.

January 10th, 2013|

Posted by AROME webmaster on January 10, 2013
Controversies in loco-regional treatment: Post-mastectomy radiation for pT2-pT3N0 breast cancer arguments in favour. Valli MC; on behalf of AROME. Crit Rev Oncol Hematol. 2010 Dec 4.PMID:21134765

Combined hormone therapy and radiation therapy for locally advanced prostate cancer

January 10th, 2013|

Posted by AROME webmaster on January 10, 2013
Combined hormone therapy and radiation therapy for locally advanced prostate cancer.Bolla M, Laramas M; on behalf of AROME. Crit Rev Oncol Hematol. 2010 Dec 8.PMID:21144766

Future challenges in head and neck cancer: From the bench to the bedside?

January 10th, 2013|

Posted by AROME webmaster on January 10, 2013
Future challenges in head and neck cancer: From the bench to the bedside? Calabrese L, Ostuni A, Ansarin M, Giugliano G, Maffini F, Alterio D, Rocca MC, Petralia G, Bruschini…